Return to Medical Topics Home Page                   

Non-Drug Approaches to Diabetes - Bibliography

Minerals - Magnesium

Magnesium and Diabetes:  A Review.  White, JR, The Annals of Pharmacotherapy1993;27:775-780.

Hypomagnesemia in Relation to Diabetic Retinopathy.  Ceriello, A, Diabetes Care 1982;5:558-59.

Daily Magnesium Supplements Improve Glucose Handling in Elderly Subjects.  Paolisso, G, American Journal of Clinical Nutrition 1992;55:1161-67.

Improved Insulin Response and Action by Chronic Magnesium Administration in Aged NIIDM Subjects.  Paolisso, G, Diabetes Care 1989;12:265-69.

Zinc

Effect of Zinc Supplementation on Serum Glucose, Insulin, Glucagon, Glucose-6-Phosphatase, and Mineral Levels in Diabetics.  Hegazi, SM, Journal of Clinical and Biochemical Nutrition 1992;12:209-15.

Diabetes Mellitus - Impaired Wound Healing from Zinc Deficiency.  Engel, ED, Journal of the American Podiatry Association 1981;71:536-44.

Potassium

Prevention of the Glucose Intolerance of Thiazide Diuretics by Maintenance of Body Potassium.  Helderman, JH, Diabetes 1983;32:106-11.

Iron overload

Desferozamine Therapy in High-Ferritin Diabetes.  Cutler, P, Diabetes 1989;38:1207-10.

Prevalence of genetic hemochrmatosis among diabetic patients.  Phelps, G, The Lancet 1989, July 29:233-34.

Trace Minerals

Chromium

Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.  Anderson, RA, Diabetes 1997;46:1786-91

Nutritional Factors Influencing the Glucose/Insulin System:  Chromium.  Anderson, RA, Journal of the American College of Nutrition 1997;16:404-10.

Chromium Supplementation for Gestational Diabetic Women Improves Glucose Tolerance and Decreases Hyperinsulinemia.  Jovanic-Peterson, L, 1263

Vanadium

Oral Vanadyl Sulfate Improves Insulin Sensitivity in NIDDM but Not in Obese Nondiabetic Subjects.  Halberstam, M, Diabetes 1996;45:659-66.

Effects of Vanadyl Sulfate on Carbohydrate and Lipid Metabolism in Patients With Non-Insulin Dependent Diabetes Mellitus.  Metabolism 1996;45:1130-35.

Lithium

Assisting Effects of Lithium on Hypoglycemic Treatment in Patinets with Diabetes.  Min, H, Biological Trace Element Research 1997;60:131-37.

Fiber

Decrease in Postprandial Insulin and Glucose Concentrations by Guar and Pectin.  Jenkins, DJ, Annals of Internal Medicine 1997;86:20-23.

Lipid- and Glucose-Lowering Efficacy of Plantage Psyllium in Type II Diabetes.  Rodrigues-Moran, Martha, Journal of Diabetes and Its Complications 1998;12:273-78.

Amino acids

Taurine

Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus:  effects of taurine supplementation.  Franconi, F, American Journal of Clinical Nutrition 1995;61:1115-9.

Arginine

Effects of low-dose L-arginine on insulin-mediated vasodilatation and insulin sensitivity.  Wascher, TC, European Journal of Clinical Investigation 1972;27:690-95.

Antioxidants - Vitamin C

In Vitro and In Vivo Reduction of Erythrocyte Sorbitol by Ascorbic Acid.  Vinson, JA, Diabetes 1989;38:1036-41.

Magnesium and Ascorbic Acid Supplementation in Diabetes Mellitus.  Eriksson, Johan, Annals of Nutrition and Metabolism 1995;39:217-23.

Low Plasma Ascorbate Levels in Pbbatients with Type 2 Diabetes Mellitus Consuming Adequate Kietary Vitamin C.  Sinclair, AJ, Diabetic Medicine 1994;11:893-98.

Vitamin C:  An Aldose Reductase Inhibitor that Normalizes Erythrocyte Sorbitol in Insulin-Dependent Diabetes Mellitus.  Cunningham, JJ, Journal of the American College of Nutrition 1994;13:344-50.

Vitamin E

Pharmacologic doses of vitamin E improve insulin action in healthy subjects and non-insulin dependent diabetic patients.  Paolisso, G, American Journal of Clinical Nutrition 1993;57:6506.

Vitamin E Reduction of Protein Glycosylation in Diabetes Ceriello, A, Diabetes Care 1991;14:68-72.

Chronic intake of pharmacological doses of vitamin E might be useful in the therapy of elderly patients with coronary heart disease.  Paolisso, G, American Journal of Clinical Nutrition 1995;61:848-52.

Increased risk of non-insulin dependent diabetes mellitus at low plasma vitamin E concentration:  a four year follow up study in men.  Salonen, JT, British Medical Journal 11995;311:1124-27.

Vitamins - Biotin

Therapeutic Evaluation of the Effect of Biotin on Hyperglycemia in Patients with Non-Insulin Dependent Diabetes Mellitus.  Maebashi, M, Journal of Clinical and Biochemical Nutrition 1993;14:211-218.

Biotin Status and Plasma Glucose in Diabetes.  Coggeshall, JC, Annals of the New York Academy of Sciences 389-92.

B12

Vitamin B12 and Retinopathy in Juvenile Diabetics.  Kornerup, Tore, Acta Pediatrica 1958;47:646-51.

The use of Vitamin B12 in the Management of the Neurologic Manifestations of Diabetes Mellitus, with Notes on the Administration of Massive Doses.  Sancetta, SM,

Herbal Therapies - Gymnema sylvestre

Antidiabetic effect of a leaf extreact from Bymnema sylvestre in non-insulin dependent diabetes mellitus patients.  Baskaran, B, Journal of Ethnopharmacology 1990;30:295-305.

Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin dependent diabetes mellitus.  Shanmugasundaram, G, Journal of Ethnopharmacology 1990;30:281-94.

Bitter Melon

Clinical Trial in Patients with Diabetes Mellitus of an Insulin-like Compound Obtained from Plant Source.  Baldwa, VS, Upsala Journal of Medical Science 1977;82:39-41.

Antidiabetic and Adaptogenic Properties of Momordica charantia Extract:  An Experimental and Clinical Evaluation.  Srivastava, Y, Phytotherapy Research 1993;7:285-89.

Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes.  Welihinda, J, Journal of Ethnopharmacology 1986;17:277-82.

Bitter Melon(Mamordica charantia).  Cunnick, J, Journal of Naturopathic Medicine 1993;4:16-21.

Aloe vera

Antidiabetic action of Aloe vera L. juice. I.  Clinical trial in new cases of diabetes mellitus.  Yongchaiyudha, S, Phytomedicine 1996;3:241-43.

Antidiabetic action of Aloe vera L. juice. II.  Clinical trial in diabetes mellitus patients in combination with glibenclamide.  Phytomedicine 1996;3:245-48.

The Antidiabetic Activity of Aloes:  Preliminary Clinical and Experimental Observations.  Ghannam, N, Hormone Research 1986;24:288-94.

Eleotin

The New Canadian Therapeutic Herbal Tea for Non-Insulin-Dependent Diabetes Mellitus.  Walker, M, Townsend Letter for Doctors and Patients May 19992-66.

Glycosaminoglycans

Glycosaminoglycans Delay the Progresion of Nephropathy in NIDDM.  Solini, A, Diabetes Care 1997;20:819-23.

Diabetic Neuropathy

A Benfotiamine-vitamin B combination in treatment of diabetic polyneuropathy.  Stracke, H, Experimental and Clinical Endocrinology & Diabetes 1996;104:311-16.

Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant a-lipoic acid.  Ziegler, D, Diabetologia 1995;38:1425-33.

a-Lipoic acid in the Treatment of Diabetic Peripheral and Cardiac Autonomic Neuropathy.  Ziegler, D, Diabetes 1997;46:S62-66.

Treatment of Painful Diabetic Neuropathy With Topical Capsacin.  The Capsacin Study Group, Archives of Internal Medicine 1991;151:2225-29.

Long-Term Effects of Eicosapentaenoic Acid on Diabetic Peripheral Neuropathy and Serum Lipids in Patients With Type II Diabetes Mellitus.  Okuda, Y, Journal of Diabetes and Its Complications 1996;10:280-87.

Diet

Utility of a Short-Term 25% Carbohydrate Diet on Improving Glycemic Control in Type 2 Diabetes Mellitus.  Guitierrez, M, Journal of the American College of Nutrition 1998;17:595-600.

Regression of Diabetic Neuropathy with Vegan Diet.  Crane, MG, 926 P-28

High-Fiber Diets in the Treatement of Diabetes Mellitus.  Miranda, PM, Annals of Internal Medicine 1978;88:482-86.

High-carbohydrate, high-fiber diets for insulin-treated men with diabetes mellitus.  Anderson, JW, The American Journal of Clinical Nutrition 1979;32:2312-21.

Effects of Caloric Restriction and Weight Los on Glycemic Control, Insulin Release and Resistance, and Atherosclerotic Risk in Obese Patients with Type II Diabetes Mellitus.  Hughes, TA, The American Journal of Medicine 1984;77:7-17.

Fructose and insulin sensitivity in patients with type 2 diabetes.  Koivisto, VA, Journal of Internal Medicine 1993;233:145-53.

Exercise

Increased Insuliln Receptors after Exercise in Patients with Insulin-Dependent Diabetes Mellitus.  Pedersen, O, The New England Journal of Medicine 1980;302:886-92.

Nicotinamide

Meta-Analysis of Nicotinamide Treatment in Patients with Recent-Onset IDDM.  Pozzillit, P, Diabetes Care 1996;19:1357-63.

Nicotinamide May Extend Remission Phase in Insulin-Dependent Diabetes.  Vague, P, The Lancet, March 14, 1987:619-20.

Can Niacinamide Prevent or Reverse Type I Diabetes-Editorial.  Murray, MT, Natural Medicine April 1998:1-3.

Nicotiamide and insulin secretion in normal subjects.  Bingley, RJ, Diabeologia 1993;36:675-77.

Prevention or delay of Type I (insulin-dependent diabetes mellitus in children using nicotinamide.  Elliot, RB, Diabetologia 1991;34:362-65.

Nicotinamide improves insulin secretion and metabolic control in lean type 2 diabetic patients with secondary failure to sulfonylureas.  Polo, V, Acta Diabetologia 1998;35:61-64.

Review Articles

Diabetes Mellitus.  Murray, MT, Natural Medicine April 1998:4-21.

Nutritional Regulation of Blood Glucose.  Gaby, AR,

Miscellaneous

Fasting Blood Glucose:  An Underestimated Risk Factor for Cardiovascular Death.  Bjornholt, JV, Diabetes Care 1999;22:45-49.

Comparison of Coronary Bypass Surgery with Angioplasty in Patients with Multivessel Disease.   BARI Investigators, The New England Journal of Medicine 1996;335:217-25.

Influence of Diabetes Mellitus on Early and Late Outcome After Percutaneous Transluminal Coronary Angioplasty.  Stein, B, Circulation 1995;91:979-89.

Sulfonylurea Drugs Increase Early Mortality in Patients With Diabetes Mellitus After Direct Angioplasty for Acute Myocardial Infarction.  Garratt, KN, Journal of the American College of Cardiology 1998;33:119-24.

A Study of the Effects of Hypoglycemic Agents on Vascular Complication in Patients with Adult-onset Diabetes - Mortality Results.  Meinhart, CL, Diabetes 1975;19(Suppl.2):789-830.

Prevalence and Mortality of Acute Myocardial Infarction in Patients with Diabetes.  Rytter, L, Diabetes Care 1985;8:230-34.